DIY Home Remedies for Colon Cleanser The colon is a part of the digestive system and is responsible for extracting the water and salt to maintain body’s electrolyte balance, from waste, prior to release. The colon can be clogged due to waste clinging to its walls. This can cause: headaches, low energy level, vomiting, weight gain, skin allergy, constipation, joint pains, indigestion, fatigue, diarrhea, vision problems, loss of memory,